Preheat your oven to 425°F (220°C) and line a baking sheet with parchment paper, lightly coating it with olive oil spray or a small amount of olive oil.
In a mixing bowl, combine the grated Parmesan, garlic powder, onion powder, sea salt, black pepper, oregano, and smoked paprika until well mixed.
Dip each zucchini round into the whisked egg, allowing excess to drip off, then roll it in the Parmesan mixture, pressing slightly to adhere.
Arrange the coated zucchini rounds on the prepared baking sheet in a single layer, ensuring they do not touch.
Sprinkle the panko breadcrumbs evenly over the top of the zucchini rounds for added crunch.
Bake in the oven for 20-25 minutes, or until the zucchini is tender and the tops are golden brown and crispy.
Allow the zucchini bites to cool for a few minutes before serving warm.